Case Study: April 2014

History

  • A 50 year old male presents with a foreign body over the bulbar conjunctiva associated with inflammation.
  • The foreign body is removed and sent for histology.
  • See figures 1,2,3.

Questions

  1. What does fig 1 show?
  2. What is seen in fig 2 (note-this is just a H&E stain)
  3. Fig 3 is a Masson Fontana-what does the arrow indicate?
  4. What is the diagnosis?
Click to show answers
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  1. Foreign body with acute inflammation
  2. These are pigmented fungi
  3. The fungi contain melanin pigment.
  4. This is a foreign body associated with phaeohyphomycosis fungal implantation.
  • These fungi have melanin in their walls and are septate and branching. The common phaehyphomycoses to affect humans include: Exophilia, Phialophora, Wangiella, Bipolaris, Exserohilum, Cladophialophora, Aureobasidium, Cladosporium, Curvularia and Alternaria.