Case Study: April 2014


  • A 50 year old male presents with a foreign body over the bulbar conjunctiva associated with inflammation.
  • The foreign body is removed and sent for histology.
  • See figures 1,2,3.


  1. What does fig 1 show?
  2. What is seen in fig 2 (note-this is just a H&E stain)
  3. Fig 3 is a Masson Fontana-what does the arrow indicate?
  4. What is the diagnosis?
Click to show answers
  1. Foreign body with acute inflammation
  2. These are pigmented fungi
  3. The fungi contain melanin pigment.
  4. This is a foreign body associated with phaeohyphomycosis fungal implantation.
  • These fungi have melanin in their walls and are septate and branching. The common phaehyphomycoses to affect humans include: Exophilia, Phialophora, Wangiella, Bipolaris, Exserohilum, Cladophialophora, Aureobasidium, Cladosporium, Curvularia and Alternaria.