Case Study: August 2011


A 60 year old man, with hypertension and a past history of an intracranial tumour presents with angle closure glaucoma and an intraocular mass.

On examination the eye is blind and painful. The eye is enucleated.

See figures.


  1. What are the key features of the choroidal mass?
  2. What is the differential?
  3. What is the diagnosis?
Click to show answers
  1. Clear cells with a vascular matrix.
  2. Metastatic clear cell carcinoma (renal, endocrine sites), primary clear cell melanoma and primary haemangioblastoma (in context of possible VHL, given
    the patient’s hypertension and previous intracranial mass).
  3. The patient had a renal mass and the diagnosis is metastatic clear cell renal carcinoma.