Case Study: December 2009

A 25 year-old male presented with bilateral bulbar conjunctival gelatinous lesions, hidden under the lower lids. The patient had asthma. No retroviral diseases. No medications.

Figure 1 shows histology of one of the gelatinous lesions.

Figure 2 shows the stroma underlying the lesion in Figure 1.


1. What does Figure 1 illustrate?
2. What is seen in Figure 2
3. What is unusual about the history?

Click to show answers
  1. Conjunctival in-situ squamous carcinoma (CIN 3)
  2. Eosinophils
  3. Young age for presentation of ocular surface squamous neoplasia, bilateral and not sun exposed (under lower lids).


Conjunctival intra-epithelial neoplasia occurring in young patients with asthma. Rundle P, Mudhar HS, Rennie I. Eye (Lond). 2009 Dec 4.