Case Study: December 2016


A 55 year-old male present with a 2mm, smooth, brown pigmented nodule on the lower lid that has been present for 2 years. The lesion is excised and sent for histopathological examination.

Figure 1 shows a low power image.

Figure 2 shows a higher power of the lining of the lesion


1. What are the main features of the pathology seen in figures 1 and 2?

2. What is the pigment in figure 1?

3. What is the diagnosis?

4. Which syndromes are associated with this lesion?


Click to show answers


1. This is a cyst lined by bilayered epithelium containing greyish pigment.

2. This could be lipofuscin, melanin, iron or drug pigment.

3. Ductal hidrocystoma / cyst of Moll. Whether these are eccrine or apocrine is a moot point.

4. Sydromes that are associated with multiple ductal hidrocystoma include Schopf-Schulz-Passarge, Goltz-Gorlin and Grave’s disease.