Case Study: February 2017

History A 45 year old male presents with bilateral upper lid dermatochalasia and undergoes bilateral blepharoplasties. His medical history includes rheumatoid arthritis.

Fig 1-skin

Fig 2-Toluidine blue stain.

Questions

1. What does figure 1 show?

2. What does figure 2 show?

3. What is the hitopathological reaction pattern?

4. Is there any relevance to the patient’s past medical history?

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Answers

1. Rather ‘oedematous’ skin at low power.

2. Metachromatic mucin (purple stringy material).

3. Dermal / cutaneous mucinosis

4. Secondary dermal mucinoses are associated with autoimmune connective tissue disorders.

References

http://www.dermnetnz.org/topics/cutaneous-mucinoses/

http://www.pcds.org.uk/clinical-guidance/mucinoses