Case Study: January 2011

A 25 year old male with visual disturbance.

B-scan shows a large choroidal mass.


See figures 1,2 and 3


  1. What is the histogenesis of the cells in fig 2?
  2. What does fig 3 show?
  3. What is the likeliest diagnosis?
  4. What happens in around 1% of these lesions?
Click to show answers
  1. Polygonal melanocytic cells, packed full of oval to circular melanosomes, with bland central nuclei.
  2. Necrosis.
  3. Benign melanocytoma. Necrosis is permissible as is transcleral invasion.
  4. They can transform into melanoma.