A 45 year old woman presents with a ciliary body mass.
This undergoes fine needle aspiration cytology.
What is the differential diagnosis based on the cytology?
The cells were positive for Melan A and negative for cytokeratins. What is the diagnosis?
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The differential includes melanoma, melanocytoma or pigmented adenoma.
The cells have bland nuclei, low N/C ratios and a cytoplasm packed with melanosomes of equal size and distribution. This is a good example of a melanocytoma. These a cytokeratin negative (unlike adenomas of the ciliary body).