Case Study: May 2010


These are micro images of an incidental finding in the vitreous, of an enucleation specimen, performed for uveal melanoma.


1. What is the incidental finding and what do you see on this cytology preparation?

Click to show answers
  1. There is an amorphous body, surrounded by foreign body giant cells.
    Note how the amorphous body is refractile on polarisation.
    This is asteroid hyalosis.


Kador PF, Wyman M. Asteroid hyalosis: pathogenesis and prospects for prevention.Eye (Lond). 2008 Oct;22(10):1278-85