Case Study: November 2010

History

A 25 year old male present with visual disturbance. Examination reveals a ciliary body mass. The eye is enucleated.

Figure 1-low power H&E
Fig 2 and Fig 3 are higher power H&E’s

Questions

  1. What histological features do Figs 2 and 3 reveal?
  2. What is the diagnosis and differential?
  3. On Fig 1 what has the tumour caused?
Click to show answers
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  1. Fantastic Verocay bodies.
  2. Ciliary body schwannoma. The differential includes melanoma and leiomyoma.
  3. Limbal staphyloma, iris displacement, lens dislocation, ciliary body effacement.

References

DONOVAN BF. Neurilemoma of the ciliary body.
AMA Arch Ophthalmol. 1956 May;55(5):672-5.

Smith PA, Damato BE, Ko MK, Lyness RW Anterior uveal neurilemmoma–a rare neoplasm simulating malignant melanoma.
Br J Ophthalmol. 1987

Küchle M, Holbach L, Schlötzer-Schrehardt U, Naumann GO.
Schwannoma of the ciliary body treated by block excision.
Br J Ophthalmol. 1994 May;78(5):397-400