Case Study: October 2011


A 20 year old male with a Coats disease presents with a fluid level in the anterior chamber.

This is tapped and sent off for cytological evaluation.

See figure.


  1. What is seen?
  2. What is the diagnosis?
Click to show answers
  1. Overlapping rhomboidal crystals of cholesterol
  2. Cholesterolosis bulbi in the setting of Coats disease.


Coats’ disease as a cause of anterior chamber cholesterolosis. Shields JA, Eagle RC Jr, Fammartino J, Shields CL, De Potter P.Arch Ophthalmol. 1995 Aug;113(8):975-7

Cholesterolosis Bulbi of the Anterior Chamber in Coats Disease.Gupta N, Beri S, D’souza P. J Pediatr Ophthalmol Strabismus. 2009; 25:1-3.