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Case Study: September 2013
History
- A 10 year old African male presents with a cream nodule at the lateral bulbar conjunctiva, towards the lateral canthus, of 6 months duration. The lesion is increasing in size.
- The lesion is excised and sent of histology.
- See figures.
Questions
- What does Fig 1 show?
- What does Fig 2 show?
- Which immunohistochemical stain has been performed in Fig 3 and what does it illustrate?
- What is the diagnosis?
Click to show answers
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- At this scanning power, there are light and dark zones on the H and E, with lymphocytes predominating in the dark zones.
- Fig 2 shows histiocyte-type cells, plasma cells and lymphocytes.
- This is an S100 stain. The histiocyte type cells show emperipolesis, better than that seen in Fig 2.
- This is conjunctival Rosai-Dorfman disease.
